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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RPL5 All Species: 52.73
Human Site: Y66 Identified Species: 77.33
UniProt: P46777 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46777 NP_000960.2 297 34363 Y66 D I I C Q I A Y A R I E G D M
Chimpanzee Pan troglodytes XP_513564 406 45547 Y175 D I I C Q I A Y A R I E G D M
Rhesus Macaque Macaca mulatta XP_001092402 249 28816 K33 V K N K A Y F K R Y Q V K F R
Dog Lupus familis XP_537074 247 28053 H31 I V C A A Y A H E L P K Y G V
Cat Felis silvestris
Mouse Mus musculus P47962 297 34382 Y66 D I I C Q I A Y A R I E G D M
Rat Rattus norvegicus P09895 297 34440 Y66 D I I C Q I A Y A R I E G D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515074 357 40536 Y126 D I I C Q I A Y A R I E G D M
Chicken Gallus gallus P22451 297 34073 Y66 D I I C Q I A Y A R I E G D M
Frog Xenopus laevis P15125 296 34087 Y66 D I I C Q I A Y A R I E G D M
Zebra Danio Brachydanio rerio NP_956050 297 34066 Y66 D I V C Q I A Y A K I E G D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9W5R8 299 34018 Y66 D I T V Q I A Y A R I E G D R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P49405 293 33368 Y66 D V V A Q L A Y S K I E G D V
Sea Urchin Strong. purpuratus XP_001177830 296 34057 Y67 N I T C Q V A Y A K L E G D V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P49227 301 34418 S66 D I V A Q I V S A S I A G D I
Baker's Yeast Sacchar. cerevisiae P26321 297 33724 S66 D I I C Q I I S S T I T G D V
Red Bread Mold Neurospora crassa O59953 301 34393 S66 D I I L Q I V S S E I T G D K
Conservation
Percent
Protein Identity: 100 73.1 76 82.8 N.A. 98.3 98.6 N.A. 81.5 95.2 91.5 84.8 N.A. 67.2 N.A. 58.2 73
Protein Similarity: 100 73.1 76.4 83.1 N.A. 99.3 99.6 N.A. 82.6 98.6 95.9 94.9 N.A. 82.6 N.A. 75.4 84.8
P-Site Identity: 100 100 0 6.6 N.A. 100 100 N.A. 100 100 100 80 N.A. 80 N.A. 53.3 60
P-Site Similarity: 100 100 0 33.3 N.A. 100 100 N.A. 100 100 100 93.3 N.A. 80 N.A. 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 55.1 48.8 51.5
Protein Similarity: N.A. N.A. N.A. 71.4 67 71.7
P-Site Identity: N.A. N.A. N.A. 53.3 60 53.3
P-Site Similarity: N.A. N.A. N.A. 66.6 73.3 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 13 0 75 0 69 0 0 7 0 0 7 % A
% Cys: 0 0 7 63 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 82 0 0 0 0 0 0 0 0 0 0 0 0 88 0 % D
% Glu: 0 0 0 0 0 0 0 0 7 7 0 69 0 0 0 % E
% Phe: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 88 7 0 % G
% His: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % H
% Ile: 7 82 57 0 0 75 7 0 0 0 82 0 0 0 7 % I
% Lys: 0 7 0 7 0 0 0 7 0 19 0 7 7 0 7 % K
% Leu: 0 0 0 7 0 7 0 0 0 7 7 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % P
% Gln: 0 0 0 0 88 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 50 0 0 0 0 13 % R
% Ser: 0 0 0 0 0 0 0 19 19 7 0 0 0 0 0 % S
% Thr: 0 0 13 0 0 0 0 0 0 7 0 13 0 0 0 % T
% Val: 7 13 19 7 0 7 13 0 0 0 0 7 0 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 69 0 7 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _